Los Angeles Chargers Odds, Moneylines, Spreads and Futures Markets

The Los Angeles Chargers odds show us that bookies are confident in this team. And why shouldn’t they be? QB Justin Herbert is a bona fide superstar with NFL MVP potential. Plus, the LA defense is loaded with talent.

Let’s find out together if Los Angeles has a real shot at making a playoff run. We’ll look at what the latest betting odds tell us and offer you analysis on LA’s chances this season.

Los Angeles Chargers Odds This Week

The Los Angeles Chargers odds this week are pretty clear-cut: they’re massive favorites against Arizona. FanDuel gives them an 85.7% chance of winning the game (which really says more about how disadvantaged the Cardinals are in this matchup).

• Moneyline: Los Angeles Chargers -600 / Arizona Cardinals +450
• Spread: Los Angeles Chargers -10.5 (-110) / Arizona Cardinals +10.5 (-110)
• Over/Under: 46.5 points (-110/-110)

We’re pretty confident that the NFL Odds are correct with this one. And here’s why: Los Angeles won 11 games in 2025, and Arizona only won three. The gap in talent here is pretty stark — plus the Chargers are a top NFL contender entering the season.

Los Angeles Chargers Odds to Win Super Bowl 61

The Los Angeles Chargers odds to win the Super Bowl are better than we expected. Despite postseason struggles for the past few decades, bookies are offering +1700 on LA winning an NFL championship. Only four other teams are ahead of them in the early odds.

• FanDuel: +1600
• DraftKings: +1700
• BetMGM: +1700

The current Super Bowl Odds are very optimistic about Los Angeles this season. But we’d be cautious here because the Chargers have never won it all. The team played in a Super Bowl once before, in the 1994 season, losing to San Francisco in that game.

The NFL Win Totals also indicate that Los Angeles is in a prime position to make the playoffs. Bookies are projecting them to win roughly 10 or more games, which could also be enough for LA to capture the AFC West.

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Los Angeles Chargers Odds to Make Playoffs

The Los Angeles Chargers odds to make the playoffs put them squarely in the hunt. Bookies like FanDuel and DraftKings are telling us that an LA postseason berth is very much on the table.

• FanDuel: -160
• DraftKings: -170
• BetMGM: -185

Our first impression here is that the preseason NFL Playoff Odds got it right. The Chargers have made the playoffs in four of the past eight seasons. Plus, the Chargers have won 11 games in back-to-back seasons.

You also have to consider the NFL MVP Odds, which indicate that QB Justin Herbert is a potential sleeper pick at +1000. And honestly, with a career passer rating of 96.3, he’s not a bad option for MVP.

Los Angeles Chargers Odds to Win Division

The Los Angeles Chargers odds to win the division indicate that there’s a three-way race. LA is up there with Kansas City and Denver as legitimate frontrunners to claim the AFC West.

• FanDuel: +190
• DraftKings: +190
• BetMGM: +185

The AFC West Odds tell us that the division is wide open. However, the biggest thing to consider here is that the Chargers haven’t won the AFC West in 17 seasons. But they could break that bad luck spell this year because the team’s current roster is that good.

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More Los Angeles Chargers Betting Markets

The preseason Los Angeles Chargers betting odds cover the Super Bowl, playoffs, etc. But as the season is underway, you can also bet on moneylines, point spreads, and over/unders involving every matchup.

We’d like to discuss all the various Los Angeles Chargers odds that don’t involve preseason markets. We’ll explain how they work and show you how much you can profit from them.

Los Angeles Chargers Moneylines

Moneylines are very straightforward: you must predict a winner or loser between two teams going head-to-head. In Week 1, the Chargers are -600 to defeat the Cardinals, which means they have a huge advantage according to the early odds.

To win $100 from picking the Chargers to win, you’d have to bet $600 (LA would have to win the game too, of course). That’s a lot of cash you'll have to wager, but that’s the price you pay since Los Angeles is a huge favorite.

Los Angeles Chargers Spreads

The Best NFL Betting Sites also offer spreads on Los Angeles in Week 1 against Arizona. This type of bet requires you to predict a certain team winning or losing by a certain number of points.

Los Angeles is a 10.5-point favorite against Arizona at -110 odds. If you pick Los Angeles to cover the spread, the Chargers would have to win by more than 10.5 points for your wager to pay out. You’d also have to wager $110 to win $100.

Los Angeles Chargers Totals (Over/Under)

Point totals involve the combined score of two NFL teams facing each other. Bookies in Week 1 are offering -110 odds on over 46.5 points and -110 odds on the under as well.

Picking the over will earn you $100 with a $110 bet. To win, the Chargers and Cardinals would have to combine for more than 46.5 points before the game ends.

Keep in mind that NFL Betting Promos involving odds boosts can increase your winnings on point totals. These are handicap bets, which limit you in terms of how much you can earn from them.

Los Angeles Chargers Props

Props are wagers involving individual and collective player performances (not final scores). You can make money from predicting how many yards Justin Herbert will throw for and other single-game statistical outcomes. A few examples include:

• Just Herbert to throw for more or less than 219.5 passing yards
• Ladd McConkey to catch for more or less than 6.5 receptions
• Derwin James to finish the game with an interception

With NFL Betting Apps, you can pick your favorite player props via your smartphone. It’s like having a sportsbook inside your pocket: you can predict and choose which players will have a breakout performance (and win money from it) whenever you’re away from home.

Los Angeles Chargers Prediction Markets

The preseason Los Angeles Chargers odds involve bookies who determine the prices. But with prediction trading, the process is much different. It’s you and other traders who set the market.

Let’s say you trade on Los Angeles versus Arizona for Week 1. The price for a ‘Yes’ contract (the Chargers winning) is $0.75 per share, which is a 75% probability. You’d have to spend $75 to acquire 100 shares of this contract.

Next, let’s say Los Angeles wins the game. The payout for this contract is $25 when you purchase 100 shares. Here’s how it works: $1 - $0.75 = $0.25 and 100 x $0.25 = $25.

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Los Angeles Chargers Odds FAQ